Where does Filitra 40 Mg absorption occur in the body?
Filitra 40 mg contains vardenafil as its active ingredient, and it is primarily absorbed in the gastrointestinal (GI) tract after oral administration. Vardenafil, like other medications in the same class (phosphodiesterase type 5 inhibitors), is absorbed through the lining of the stomach and intestines into the bloodstream. Once absorbed, vardenafil is distributed throughout the body via the bloodstream. It reaches peak plasma concentrations within about 30 to 120 minutes after oral administration. Food intake, particularly high-fat meals, may delay the absorption of vardenafil, so it is often recommended to take Filitra 40 mg on an empty stomach for optimal absorption and effectiveness. After absorption, vardenafil is metabolized in the liver by the enzyme CYP3A4 into its primary metabolite. The metabolites are then eliminated primarily through the feces (approximately 91-95%) and, to a lesser extent, through the urine (approximately 2-6%). It's important to note that absorption of vardenafil can vary among individuals and may be influenced by factors such as age, liver function, gastrointestinal health, and concomitant use of certain medications. Additionally, absorption may be affected by the formulation of the medication (e.g., immediate-release tablets, orally disintegrating tablets) and whether it is taken with food or on an empty stomach.