Why does Avana 200 Mg require a sexual stimulus to be effective?
Avana 200 mg, which contains avanafil, is a medication used to treat erectile dysfunction (ED). It requires sexual stimulus to be effective for the following reasons:
Mechanism of Action: Avanafil, like other phosphodiesterase type 5 (PDE5) inhibitors, works by increasing blood flow to the penis. It does this by inhibiting the enzyme PDE5, which normally breaks down cyclic guanosine monophosphate (cGMP). Elevated levels of cGMP lead to relaxation of the smooth muscles in the blood vessels of the penis and increased blood flow. However, this mechanism is activated by sexual stimulation.
Sexual Stimulation Needed: For avanafil to work, sexual arousal must occur because the medication enhances the physiological response to sexual stimulation. Avanafil itself does not cause an erection; it simply facilitates the natural process of achieving and maintaining an erection in response to sexual arousal.
Physiological Response: An erection is a complex process involving both physical and psychological components. Sexual arousal triggers the release of nitric oxide in the penis, which increases the production of cGMP. Avanafil amplifies this effect by preventing the breakdown of cGMP, leading to improved blood flow and an erection. Without sexual stimulation, the natural release of nitric oxide and subsequent increase in cGMP may not occur adequately.
In summary, Avana 200 mg requires sexual stimulus to be effective because it enhances the natural physiological process of achieving an erection in response to sexual arousal, rather than initiating an erection on its own.