Sildigra 100 mg, containing the active ingredient Sildenafil Citrate, works to improve blood flow primarily by inhibiting an enzyme called phosphodiesterase type 5 (PDE5). Here’s a step-by-step breakdown of how it functions:
Release of Nitric Oxide: When you are sexually stimulated, the body releases nitric oxide in the penile tissue. Nitric oxide is a natural vasodilator, which helps expand blood vessels.
Inhibition of PDE5: Sildigra 100mg mg blocks the PDE5 enzyme. Normally, PDE5 breaks down cyclic guanosine monophosphate (cGMP), a molecule that regulates blood flow in the penis. By inhibiting PDE5, Sildenafil helps maintain higher levels of cGMP.
Relaxation of Blood Vessel Walls: The increased cGMP causes the smooth muscles in the blood vessel walls to relax. This leads to dilation of the blood vessels in the penile tissue, allowing for increased blood flow.
Enhanced Erection Quality: With the blood vessels expanded, more blood can enter the penis, making it easier to achieve and maintain an erection in response to sexual stimulation.
This process specifically affects blood flow to the penile region without significantly altering blood flow to other parts of the body, which is why Sildenafil is effective for treating erectile dysfunction.