Avana 100 mg (containing avanafil) is a medication used to treat erectile dysfunction (ED). It works by increasing blood flow to the penis, helping to achieve and maintain an erection during sexual stimulation. However, like other ED medications, it is important to use Avana 100 mg with caution, especially when taken alongside other medications, including other ED treatments. Here are some specific instructions:
1. Avoid Combining with Other ED Medications
Do not use Avana 100 mg with other ED medications (e.g., sildenafil [Viagra], tadalafil [Cialis], or vardenafil [Levitra]). Combining these medications can increase the risk of serious side effects, including dangerously low blood pressure, dizziness, fainting, or heart complications.
2. Nitrates
Do not take Avana 100 mg if you are using nitrates, which are medications commonly prescribed for chest pain (angina). Nitrates include drugs like nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. The combination can lead to a severe drop in blood pressure, which can be life-threatening.
3. Alpha-Blockers
Caution is needed if you are on alpha-blockers, which are often used for high blood pressure or prostate issues (e.g., tamsulosin, doxazosin). Taking Avana with these medications can lead to a sudden drop in blood pressure. If prescribed, they should be taken at different times, or your healthcare provider may adjust the doses.
4. Antihypertensives
If you are taking blood pressure medications, discuss with your doctor before using Avana 100mg. It can have an additive effect on lowering blood pressure, especially if used with certain antihypertensives (e.g., beta-blockers or calcium channel blockers).
5. Antifungal and Antibiotic Medications
Certain antifungal medications (e.g., ketoconazole, itraconazole) and antibiotics (e.g., clarithromycin, erythromycin) can increase avanafil levels in the blood, leading to potential side effects. Your doctor may need to adjust the dosage of Avana if you are taking these medications.
6. HIV Medications
Some HIV protease inhibitors (e.g., ritonavir, indinavir) can increase the levels of Avana in the body. Using these medications together requires close monitoring, and your doctor might adjust the dose of Avana to avoid side effects.
7. Alcohol and Grapefruit Juice
Limit alcohol intake while using Avana, as alcohol can enhance side effects like dizziness or fainting.
Avoid grapefruit juice since it can interfere with the metabolism of avanafil, leading to increased drug levels in your body and an elevated risk of side effects.