Iverheal 6 mg is a generic version of Ivermectin, primarily used in the treatment of parasitic infections. Its effect on the expression of matrix metalloproteinases (MMPs) in skin fibroblasts hasn't been extensively studied or well-documented in scientific literature up to my last update. However, MMPs are enzymes involved in the breakdown of extracellular matrix components in tissues, including skin. Theoretically, Iverheal 6 medications like Ivermectin could potentially affect MMP expression indirectly through various mechanisms, such as modulation of inflammatory pathways or cellular signaling cascades. Skin fibroblasts play a crucial role in maintaining skin structure and repair, and MMPs are involved in both physiological and pathological remodeling processes in the skin. To ascertain the specific effects of Iverheal 6 mg on MMP expression in skin fibroblasts, controlled laboratory studies would be needed. These studies would involve examining the direct impact of Ivermectin on MMP production and activity in cultured skin fibroblasts under various conditions mimicking both normal and pathological states of the skin.